NEW YORK — A team of researchers including an Indian American scientist has developed an "in-body GPS" system that can pinpoint the location of ingestible implants inside the body using low-power wireless signals.
Researchers from the Massachusetts Institute of Technology led by Prof. Dina Katabi developed a "ReMix" system that, in animal tests, demonstrated that it can track implants with centimeter-level accuracy.
In the future, doctors can implant sensors to track tumors or even dispense drugs using this non-invasive wireless system, the team hoped.
"We want a model that's technically feasible while still complex enough to accurately represent the human body," said Deepak Vasisht, lead author on the new paper.
"If we want to use this technology on actual cancer patients one day, it will have to come from better modeling a person's physical structure," he added.
According to the team, such systems could help enable more widespread adoption of proton therapy centers, of which there are only about 100 globally.
"One reason that (proton therapy) is so expensive is because of the cost of installing the hardware," said Vasisht, who works at MIT's Computer Science and Artificial Intelligence Laboratory.
To test ReMix, Katabi's group first implanted a small marker in animal tissues.
To track its movement, they used a wireless device that reflects radio signals at the patient, and a special algorithm to pinpoint the exact location of the marker.
The team used a wireless technology that they had previously demonstrated to detect heart rate, breathing and movement.
Interestingly, the marker inside the body does not need to transmit any wireless signal. It simply reflects the signal transmitted by a device outside the body, without needing a battery or any other external source of energy.
The ability to continuously sense inside the human body has largely been a distant dream.
"One of the roadblocks has been wireless communication to a device and its continuous localization. 'ReMix' makes a leap in this direction by showing that the wireless component of implantable devices may no longer be the bottleneck," said Romit Roy Choudhury, professor of electrical engineering and computer science at the University of Illinois, who was not involved in the research.
The team would present the paper this at the Association for Computing Machinery's Special Interest Group on Data Communications in Budapest, Turkey.